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1

VEGF and angiopoietin signaling in tumor angiogenesis and metastasis

Pipsa Saharinen, Lauri Eklund, Kristina Pulkki, Petri Bono, Kari Alitalo

Journal:

Trends in Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 1.42 MB

english, 2011

2

Lymphangiogenesis in development and human disease

Alitalo, Kari, Tammela, Tuomas, Petrova, Tatiana V.

Journal:

Year:

2005

Language:

english

File:

PDF, 743 KB

english, 2005

3

Molecular regulation of angiogenesis and lymphangiogenesis

Adams, Ralf H., Alitalo, Kari

Journal:

Nature Reviews Molecular Cell Biology

Year:

2007

Language:

english

File:

PDF, 2.28 MB

english, 2007

4

Involvement of VEGFR-2 (kdr/flk-1) but not VEGFR-1 (flt-1) in VEGF-A and VEGF-C-induced tube formation by human microvascular endothelial cells in fibrin matrices in vitro

Pieter Koolwijk, Erna Peters, Bea van der Vecht, Carsten Hornig, Herbert A. Weich, Kari Alitalo, Daniel J. Hicklin, Yan Wu, Larry Witte, Victor W.M. van Hinsbergh

Journal:

Year:

2001

Language:

english

File:

PDF, 701 KB

english, 2001

5

VEGFs and receptors involved in angiogenesis versus lymphangiogenesis

Marja Lohela, Maija Bry, Tuomas Tammela, Kari Alitalo

Journal:

Current Opinion in Cell Biology

Year:

2009

Language:

english

File:

PDF, 1.95 MB

english, 2009

6

Expression of the Vascular Endothelial Growth Factor C Receptor VEGFR-3 in Lymphatic Endothelium of the Skin and in Vascular Tumors

Athina Lymboussaki, Taina A. Partanen, Birgitta Olofsson, Judith Thomas-Crusells, Christopher D.M. Fletcher, Robert M.W. de Waal, Arja Kaipainen, Kari Alitalo

Journal:

The American Journal of Pathology

Year:

1998

Language:

english

File:

PDF, 2.58 MB

english, 1998

7

The lymphatic vasculature in disease

Journal:

Nature Medicine

Year:

2011

Language:

english

File:

PDF, 7.42 MB

english, 2011

8

SnapShot: Angiopoietins and Their Functions

Saharinen, Pipsa, Leppänen, Veli-Matti, Alitalo, Kari

Journal:

Year:

2017

Language:

english

File:

PDF, 3.62 MB

english, 2017

9

Lack of lymphatic vascular specificity of vascular endothelial growth factor receptor 3 in 185 vascular tumors

Taina A. Partanen, Kari Alitalo, Markku Miettinen

Journal:

Year:

1999

Language:

english

File:

PDF, 722 KB

english, 1999

10

Localization of VEGF-B in the mouse embryo suggests a paracrine role of the growth factor in the developing vasculature

Karin Aase, Athina Lymboussaki, Arja Kaipainen, Birgitta Olofsson, Kari Alitalo, Ulf Eriksson

Journal:

Developmental Dynamics

Year:

1999

Language:

english

File:

PDF, 1.01 MB

english, 1999

11

Vascular endothelial growth factors VEGF-B and VEGF-C

Vladimir Joukov, Arja Kaipainen, Michael Jeltsch, Katri Pajusola, Birgitta Olofsson, Vijay Kumar, Ulf Eriksson, Kari Alitalo

Journal:

Journal of Cellular Physiology

Year:

1997

Language:

english

File:

PDF, 128 KB

english, 1997

12

Vascular endothelial growth factor (VEGF)-C synergizes with basic fibroblast growth factor and VEGF in the induction of angiogenesis in vitro and alters endothelial cell extracellular proteolytic activity

Michael S. Pepper, Stefano J. Mandriota, Michael Jeltsch, Vijay Kumar, Kari Alitalo

Journal:

Journal of Cellular Physiology

Year:

1998

Language:

english

File:

PDF, 689 KB

english, 1998

13

Vascularization of the mouse embryo: A study of flk-1, tek, tie, and vascular endothelial growth factor expression during development

Daniel J. Dumont, Guo-Hua Fong, Mira C. Puri, Gérard Gradwohl, Kari Alitalo, Martin L. Breitman

Journal:

Developmental Dynamics

Year:

1995

Language:

english

File:

PDF, 1.77 MB

english, 1995

14

Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85α, p55α, and p50α

Carla Mouta-Bellum, Aleksander Kirov, Laura Miceli-Libby, Maria L. Mancini, Tatiana V. Petrova, Lucy Liaw, Igor Prudovsky, Philip E. Thorpe, Naoyuki Miura, Lewis C. Cantley, Kari Alitalo, David A. Fru

Journal:

Developmental Dynamics

Year:

2009

Language:

english

File:

PDF, 11.66 MB

english, 2009

15

FLT4 Receptor Tyrosine Kinase Gene Mapping to Chromosome Band 5q35 in Relation to the t(2;5), t(5;6), and t(3;5) Translocations

Elina Armstrong, Kumar Kastury, Olga Aprelikova, Florencia Bullrich, Christian Nezelof, Jean Gogusev, John J. Wasmuth, Kari Alitalo, Steven Morris, Kay Huebner

Journal:

Genes, Chromosomes and Cancer

Year:

1993

Language:

english

File:

PDF, 780 KB

english, 1993

16

VEGF-C induced lymphangiogenesis is associated with lymph node metastasis in orthotopic MCF-7 tumors

Mirjami M-T. Mattila, Johanna K. Ruohola, Terhi Karpanen, David G. Jackson, Kari Alitalo, Pirkko L. Härkönen

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 2.18 MB

english, 2002

17

Immunodetection and quantification of vascular endothelial growth factor receptor-3 in human malignant tumor tissues

Hiroko Bando, Maren Brokelmann, Masakazu Toi, Kari Alitalo, Jonathan P. Sleeman, Bence Sipos, Hermann-Josef Gröne, Herbert A. Weich

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 303 KB

english, 2004

18

Modulating metastasis by a lymphangiogenic switch in prostate cancer

Ebba Brakenhielm, Jeremy B. Burton, Mai Johnson, Nelson Chavarria, Kouki Morizono, Irvin Chen, Kari Alitalo, Lily Wu

Journal:

International Journal of Cancer

Year:

2007

Language:

english

File:

PDF, 1.46 MB

english, 2007

19

Extracellular matrix proteins characterize human tumor cell lines

Kari Alitalo, Jorma Keski-oja, Antti Vaheri

Journal:

International Journal of Cancer

Year:

1981

Language:

english

File:

PDF, 701 KB

english, 1981

20

Expression of the c-Ha-ras and neu oncogenes in DMBA-induced, anti-estrogen-treated rat mammary tumors

Tuula Vuorio, Anni Wärri, Minna Sandberg, Kari Alitalo, Eero Vuorio

Journal:

International Journal of Cancer

Year:

1988

Language:

english

File:

PDF, 1.74 MB

english, 1988

21

Oncogene expression in small-cell lung cancer cell lines and a testicular germ-cell tumor: Activation of the N-myc gene and decreased RB mRNA

Kalle Saksela, Tomi P. Mäkelä, Kari Alitalo

Journal:

International Journal of Cancer

Year:

1989

Language:

english

File:

PDF, 894 KB

english, 1989

22

Estrogen suppression of erbB2 expression is associated with increased growth rate of ZR-75-1 human breast cancer cells in vitro and in nude mice

Anni M. Wärri, Aire M. Laine, Karin E. Majasuo, Kari K. Alitalo, Pirkko L. Härkönen

Journal:

International Journal of Cancer

Year:

1991

Language:

english

File:

PDF, 1.15 MB

english, 1991

23

Analysis of tyrosine kinase mRNAs including four FGF receptor mRNAs expressed in MCF-7 breast-cancer cells

Laura Lehtola, Juha Partanen, Lea Sistonen, Jaana Korhonen, Anni Wärri, Pirkko Härkzönen, Robert Clarke, Kari Alitalo

Journal:

International Journal of Cancer

Year:

1992

Language:

english

File:

PDF, 1.41 MB

english, 1992

24

A sub-set of immediate early mRNAs induced by tumor necrosis factor-α during cellular cytotoxic and non-cytotoxic responses

Juha Klefstrom, Eero Saksela, Kari Alitalo, Päivi J. Koskinen, Marja Jäättelä, Rodrigo Bravo

Journal:

International Journal of Cancer

Year:

1993

Language:

english

File:

PDF, 740 KB

english, 1993

25

Evidence for p15 cleavage site in myc-specific proteins of avian MC29 and OK10 viruses

Vlasta Sovová, Miloslav Trávníček, Ivo Hložánek, Hana Černá, Kari Alitalo, Antti Vaheri

Journal:

Journal of Cellular Biochemistry

Year:

1985

Language:

english

File:

PDF, 415 KB

english, 1985

26

Transforming growth factor-β does not alter interleukin-1 expression in cultured human macrophages

Mikko Hurme, Marja Sihvola, Kari Alitalo, Jorma Keski-Oja

Journal:

Journal of Cellular Biochemistry

Year:

1989

Language:

english

File:

PDF, 454 KB

english, 1989

27

Regulation by EGF is maintained in an overexpressed chimeric EGFR/neu receptor tyrosine kinase

Heikki Lehväslaiho, Lea Sistonen, Flavia DiRenzo, Juha Partanen, Paolo Comoglio, Erkki Hölttä, Kari Alitalo

Journal:

Journal of Cellular Biochemistry

Year:

1990

Language:

english

File:

PDF, 1.12 MB

english, 1990

28

Constitutively activated neu oncoprotein tyrosine kinase interferes with growth factor-induced signals for gene activation

Laura Lehtola, Lea Sistonen, Päivi Koskinen, Heikki Lehväslaiho, Kari Alitalo, Maria Flavia Di Renzo, Paolo M. Comoglio

Journal:

Journal of Cellular Biochemistry

Year:

1991

Language:

english

File:

PDF, 1.27 MB

english, 1991

29

Cell transformation by c-Ha-rasVal12 oncogene is accompanied by a decrease in histone H1° and an increase in nucleosomal repeat length

Jens Laitinen, Lea Sistonen, Kari Alitalo, Erkki Hölttä

Journal:

Journal of Cellular Biochemistry

Year:

1995

Language:

english

File:

PDF, 1.02 MB

english, 1995

30

Effects of Zn2+ ions on protein phosphorylation in epithelial cell membranes

Kari Alitalo, Jorma Keski-Oja, Paul Bornstein

Journal:

Journal of Cellular Physiology

Year:

1983

Language:

english

File:

PDF, 1.36 MB

english, 1983

31

Gene transfer into rabbit arteries with adeno-associated virus and adenovirus vectors

Marcin Gruchała, Shalini Bhardwaj, Katri Pajusola, Himadri Roy, Tuomas T. Rissanen, Ilze Kokina, Ivana Kholová, Johanna E. Markkanen, Juha Rutanen, Tommi Heikura, Kari Alitalo, Hansruedi Büeler, Seppo

Journal:

The Journal of Gene Medicine

Year:

2004

Language:

english

File:

PDF, 352 KB

english, 2004

32

Perspectives on lymphangiogenesis and angiogenesis in cancer

Tanja Holopainen, Maija Bry, Kari Alitalo, Anne Saaristo

Journal:

Journal of Surgical Oncology

Year:

2011

Language:

english

File:

PDF, 133 KB

english, 2011

33

Analysis of Tie receptor tyrosine kinase in haemopoietic progenitor and leukaemia cells

Eola Kukk, Ulla Wartiovaara, Yuji Gunji, Jaakko Kaukonen, Hans-Jörg Bühring, Irene Rappold, Marja-Terttu Matikainen, Pirkko Vihko, Juha Partanen, Aarno Palotie, Kari Alitalo, Riitta Alitalo

Journal:

British Journal of Haematology

Year:

1997

Language:

english

File:

PDF, 690 KB

english, 1997

34

Monoclonal antibodies to vascular endothelial growth factor-D block its interactions with both VEGF receptor-2 and VEGF receptor-3

Marc G. Achen, Sally Roufail, Teresa Domagala, Bruno Catimel, Edouard C. Nice, Detlef M. Geleick, Roger Murphy, Andrew M. Scott, Carol Caesar, Taija Makinen, Kari Alitalo, Steven A. Stacker

Journal:

Year:

2000

Language:

english

File:

PDF, 827 KB

english, 2000

35

Evidence of a leading role for VEGF in Bartonella henselae-induced endothelial cell proliferations

Volkhard A. J. Kempf, Bettina Volkmann, Martin Schaller, Christian A. Sander, Kari Alitalo, Tanja Rieß, Ingo B. Autenrieth

Journal:

Cellular Microbiology

Year:

2001

Language:

english

File:

PDF, 2.94 MB

english, 2001

36

Vascular Endothelial Growth Factor-C (VEGF-C) and its Receptors KDR and flt-4 are Expressed in AIDS-Associated Kaposi’s Sarcoma

Skobe, Mihaela, Brown, Lawrence F, Tognazzi, Kathi, Ganju, Ramesh K, Dezube, Bruce J, Alitalo, Kari, Detmar, Michael

Journal:

The Journal of Investigative Dermatology

Year:

1999

Language:

english

File:

PDF, 982 KB

english, 1999

37

Embryonic vascular endothelial cells are malleable to reprogramming via Prox1 to a lymphatic gene signature

Harold Kim, Vicky PKH Nguyen, Tatiana V Petrova, Maribelle Cruz, Kari Alitalo, Daniel J Dumont

Journal:

BMC Developmental Biology

Year:

2010

Language:

english

File:

PDF, 4.77 MB

english, 2010

38

Evolution of karyotypic abnormalities and C-MYConcogene amplification in human colonic carcinoma cell lines

C. C. Lin, Kari Alitalo, Manfred Schwab, Donna George, Harold E. Varmus, J. Michael Bishop

Journal:

Year:

1985

Language:

english

File:

PDF, 1.49 MB

english, 1985

39

Genesis and pathogenesis of lymphatic vessels

Michael Jeltsch, Tuomas Tammela, Kari Alitalo, Jörg Wilting

Journal:

Cell and Tissue Research

Year:

2003

Language:

english

File:

PDF, 562 KB

english, 2003

40

Current biology of VEGF-B and VEGF-C

Birgitta Olofsson, Michael Jeltsch, Ulf Eriksson, Kari Alitalo

Journal:

Current Opinion in Biotechnology

Year:

1999

Language:

english

File:

PDF, 192 KB

english, 1999

41

Basal Lamina Components in Experimentally Induced Skin Blisters.

Saksela, Olli, Alitalo, Kari, Kiistala, Urpo, Vaheri, Antti

Journal:

The Journal of Investigative Dermatology

Year:

1981

File:

PDF, 2.07 MB

1981

42

Lymphangiogenesis in development and human disease

Kari Alitalo, , Collaborators

Journal:

Experimental Dermatology

Year:

2007

Language:

english

File:

PDF, 48 KB

english, 2007

43

Insights into the Molecular Pathogenesis and Targeted Treatment of Lymphedema

ANNE SAARISTO, MARIKA J. KARKKAINEN, KARI ALITALO

Journal:

Annals of the New York Academy of Sciences

Year:

2002

File:

PDF, 4.39 MB

2002

44

A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells

Schwab, Manfred, Alitalo, Kari, Varmus, Harold E., Bishop, J. Michael, George, Donna

Journal:

Year:

1983

File:

PDF, 711 KB

1983

45

Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour

Schwab, Manfred, Alitalo, Kari, Klempnauer, Karl-Heinz, Varmus, Harold E., Bishop, J. Michael, Gilbert, Fred, Brodeur, Garrett, Goldstein, Milton, Trent, Jeffrey

Journal:

Year:

1983

File:

PDF, 597 KB

1983

46

Identification of nuclear proteins encoded by viral and cellular myc oncogenes

Alitalo, Kari, Ramsay, Gary, Bishop, J. Michael, Pfeifer, Susan Ohlsson, Colby, Wendy W., Levinson, Arthur D.

Journal:

Year:

1983

File:

PDF, 805 KB

1983

47

Amplification and enhanced expression of the c-myc oncogene in mouse SEWA tumour cells

Schwab, Manfred, Ramsay, Gary, Alitalo, Kari, Varmus, Harold E., Bishop, J. Michael, Martinsson, Tommy, Levan, Goran, Levan, Albert

Journal:

Year:

1985

File:

PDF, 626 KB

1985

48

10.1038/35067005

Jones, Nina, Iljin, Kristiina, Dumont, Daniel J., Alitalo, Kari

Journal:

Nature Reviews Molecular Cell Biology

Year:

2001

Language:

english

File:

PDF, 3.04 MB

english, 2001

49

10.1038/35074588

Bergsten, Erika, Uutela, Marko, Li, Xuri, Pietras, Kristian, Östman, Arne, Heldin, Carl-Henrik, Alitalo, Kari, Eriksson, Ulf

Journal:

Nature Cell Biology

Year:

2001

Language:

english

File:

PDF, 469 KB

english, 2001

50

10.1038/35083104

Journal:

Nature Cell Biology

Year:

2001

Language:

english

File:

PDF, 592 KB

english, 2001